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Drug Information For: METHADOSE (METHADONE) 40MG SOL TAB

Ingredient Name: METHADONE (METH-a-done)

Drug Manufacturer: MALLINCKRODT CHEM

Common Uses: This medicine is a narcotic analgesic used to treat narcotic addiction (such as heroin or morphine) along with appropriate medical services. It may also be used to treat other conditions as determined by your doctor.

Before Using This Medicine: WARNING: Methadone is to be taken by mouth only. It must not be injected. Methadone is a synthetic narcotic. Patients who are physically dependent on narcotics will go through withdrawal syndrome if given the usual dose of a narcotic antagonist such as naloxone. If a narcotic antagonist must be given, the dose must be smaller than the usual dose and it must be given with extreme care. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking sodium oxybate. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking medicines for HIV (such as efavirenz, zidovudine, or ritonavir), medicines for sleep (such as zolpidem), medicines for a mental/mood disorder (such as fluoxetine), medicines for pain (such as codeine), medicines for anxiety (such as diazepam), fluconazole, cimetidine, opioid antagonists (naltrexone), pentazocine, rifampin, tricyclic antidepressant (such as desipramine) phenothiazines (such as chlorpromazine), monoamine oxidase inhibitor (such as furazolidone, linezolid, moclobemide, phenelzine, procarbazine, selegiline, isocarboxazid, or tranylcypromine). Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, asthma, stomach problems (such as severe inflammatory bowel disease), liver problems, kidney problems, thyroid problems (such as hypothyroidism or Addison's disease), prostrate problems, urinary problems, allergies, pregnancy, or breast-feeding. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have a history of severe or persistent diarrhea (such as diarrhea due to pseudomembranous colitis or diarrhea due to poisoning), breathing problems (such as high levels of carbon dioxide in the blood due to poor ventilation in the lungs). Contact your doctor or pharmacist if you have any questions or concerns about using this medicine.

How to Use This Medicine: Follow the directions for using this medicine provided by your doctor. DO NOT SWALLOW THE TABLETS. Place the tablet in a glass and add about 4 ounces of cold water. ALLOW THE TABLET TO DISSOLVE COMPLETELY, then drink all the liquid. STORE THIS MEDICINE at room temperature in a tightly-closed container, away from heat and light. IF YOU MISS A DOSE OF THIS MEDICINE and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Cautions: DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or are allergic to any ingredient in this product. DO NOT EXCEED THE RECOMMENDED DOSE or take this medicine for longer than prescribed without checking with your doctor. Exceeding the recommended dose or taking this medicine for longer than prescribed may be habit-forming. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are taking this medicine. BEFORE YOU HAVE ANY MEDICAL OR DENTAL SURGERY OR EMERGENCY TREATMENT, tell the doctor or dentist that you are taking this medicine. Check with your doctor before drinking alcohol while taking this medicine. This medicine will add to the effects of alcohol and other depressants. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. THIS MEDICINE MAY CAUSE DIZZINESS, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. Caution should be used in the elderly since they may be more sensitive to the effects of this medicine. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. THIS MEDICINE IS EXCRETED IN BREAST MILK. IF YOU ARE OR WILL BE BREAST-FEEDING while you area using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.

Possible Side Effects: SIDE EFFECTS, that may go away during treatment, include drowsiness, dizziness, lightheadedness, sweating, weakness, dry mouth, loss of appetite, nausea, vomiting, headache, or constipation. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience mental or mood changes, vision problems, difficulty urinating, or reduced sexual desire. CONTACT YOUR DOCTOR IMMEDIATELY if you experience the following side effects feeling of warmth, slowed heartbeat, irregular heartbeat, or fainting. An allergic reaction to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

Overdose: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include cold and clammy skin; coma; incoordination; severe drowsiness; severe muscle weakness; slow heartbeat; slow, shallow, or difficult breathing; very large or very small pupils.
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